Psoriasin / S100A7 is encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. This protein is markedly over-expressed in the skin lesions of psoriatic patients, but is excluded as a candidate gene for familial psoriasis susceptibility. The exact function of this protein is not known.

Long Name

S100 Calcium Binding Protein A7

Alternate Names

PSOR1

Gene Symbol

S100A7

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Product Documents for S100A7/Psoriasin Antibody (129) [Janelia Fluor® 549]

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Product Specific Notices for S100A7/Psoriasin Antibody (129) [Janelia Fluor® 549]

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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S100A7/Psoriasin Antibody (129) [Janelia Fluor® 549]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-89814JF549

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Applications for S100A7/Psoriasin Antibody (129) [Janelia Fluor® 549]

Immunohistochemistry-Paraffin

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Background: S100A7