SAFB Antibody (6F7)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-27940

Novus Biologicals, part of Bio-Techne
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NBP3-27940
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Key Product Details

Species Reactivity

Human, Monkey, Orangutan, Primate

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 6F7

Concentration

1 mg/ml

View all SAFB Antibodies »

Product Specifications

Immunogen

SAFB monoclonal antibody was raised against amino acids 345 - 357 of SAFB (Human).

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for SAFB Antibody (6F7)

SAFB Antibody (6F7)

Immunohistochemistry: SAFB Antibody (6F7) [NBP3-27940] -

Immunohistochemistry: SAFB Antibody (6F7) [NBP3-27940] - Immunohistochemistry staining of SAFB in brain cortex tissue using SAFB monoclonal Antibody.
SAFB Antibody (6F7)

Immunohistochemistry: SAFB Antibody (6F7) [NBP3-27940] -

Immunohistochemistry: SAFB Antibody (6F7) [NBP3-27940] - Immunohistochemistry staining of SAFB in brain cortex tissue using SAFB monoclonal Antibody.

Applications for SAFB Antibody (6F7)

Application
Recommended Usage

Immunohistochemistry

10 ug/mL

Western Blot

1:1000 - 1:3000

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

No Preservative

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SAFB

SAFB encodes a DNA-binding protein that has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. This encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of the heat shock protein 27 transcription and also can act as an estrogen receptor corepressor. This gene is a candidate gene for breast tumorigenesis.

Alternate Names

glutathione S-transferase fusion protein, HAP, heat-shock protein (HSP27) estrogen response element and TATA box-bindingprotein, HETDKFZp779C1727, Hsp27 ERE-TATA binding protein, HSP27 ERE-TATA-binding protein, HSP27 estrogen response element-TATA box-binding protein, SAF-B, SAF-B1, SAFB1SAB-B1, scaffold attachment factor B, scaffold attachment factor B1

Gene Symbol

SAFB

UniProt

Q15424 (Human)

Additional SAFB Products

Product Documents for SAFB Antibody (6F7)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for SAFB Antibody (6F7)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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