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SAM68 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00010657-B01P

Novus Biologicals, part of Bio-Techne
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H00010657-B01P

Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Mouse IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

KHDRBS1 (AAH10132.1, 1 a.a. - 381 a.a.) full-length human protein. MQRRDDPAARMSRSSGRSGSMDPSGAHPSVRQTPSRQPPLPHRSRGGGGGSRGGARASPATQPPPLLPPSATGPDATVGGPAPTPLLPPSATASVKMEPENKYLPELMAEKDSLDPSFTHAMQLLTAEIEKIQKGDSKKDDEENYLDLFSHKNMKLKERVLIPVKQYPKFNFVGKILGPQGNTIKRLQEETGAKISVLGKGSMRDKAKEEELRKGGDPKYAHLNMDLHVFIEVFGPPCEAYALMAHAMEEVKKFLVPDMMDDICQEQFLELSYLNGVPEPSRGRGVPVRGRGAAPPPPPVPRGRGVGPPRGALVRGTPVRGAITRGATVTRGVPPPPTVRGAPAPRARTAGIQRIPLPPPPAPETYEEYVRNLNNVPFPST

Specificity

KHDRBS1 - KH domain containing, RNA binding, signal transduction associated 1,

Clonality

Polyclonal

Host

Mouse

Isotype

IgG

Scientific Data Images for SAM68 Antibody

Western Blot: SAM68 Antibody [H00010657-B01P]

Western Blot: SAM68 Antibody [H00010657-B01P]

Western Blot: SAM68 Antibody [H00010657-B01P] - Analysis of KHDRBS1 expression in transfected 293T cell line by KHDRBS1 polyclonal antibody. Lane 1: KHDRBS1 transfected lysate(41.91 KDa). Lane 2: Non-transfected lysate.
Immunocytochemistry/ Immunofluorescence: SAM68 Antibody [H00010657-B01P]

Immunocytochemistry/ Immunofluorescence: SAM68 Antibody [H00010657-B01P]

Immunocytochemistry/Immunofluorescence: SAM68 Antibody [H00010657-B01P] - Analysis of purified antibody to KHDRBS1 on HeLa cell. (antibody concentration 10 ug/ml)

Applications for SAM68 Antibody

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: SAM68

Recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once phosphorylated, functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain-containing proteins. Role in G2-M progression in the cell cycle. Represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP. Also acts as a putative regulator of mRNA stability and/or translation rates and mediates mRNA nuclear export Function: Isoform 3, which is expressed in growth-arrested cells only, inhibits S phase

Long Name

Src-associated in Mitosis 68 kDa Protein

Alternate Names

KHDRBS1, p62, p68

Entrez Gene IDs

10657 (Human)

Gene Symbol

KHDRBS1

Additional SAM68 Products

Product Documents for SAM68 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SAM68 Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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