SAP18 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-89385

Novus Biologicals, part of Bio-Techne
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NBP1-89385
NBP1-89385-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (99%), Rat (99%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all SAP18 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: VTQEEIKKEPEKPIDREKTCPLLLRVFTTNNGRHHRMDEFSRGNVPSSELQIYTWMDATLKELTSLVKEVYPEARKKGTHFNFAIVFTDVKRPGYRVKEIGSTMSGRKGTDDSMTLQSQKFQIGDYLDIAITPPNRAPP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SAP18 Antibody

Immunocytochemistry/ Immunofluorescence: SAP18 Antibody [NBP1-89385]

Immunocytochemistry/ Immunofluorescence: SAP18 Antibody [NBP1-89385]

Immunocytochemistry/Immunofluorescence: SAP18 Antibody [NBP1-89385] - Staining of human cell line A-431 shows localization to nucleoplasm & nuclear bodies.
Immunohistochemistry-Paraffin: SAP18 Antibody [NBP1-89385]

Immunohistochemistry-Paraffin: SAP18 Antibody [NBP1-89385]

Immunohistochemistry-Paraffin: SAP18 Antibody [NBP1-89385] - Staining of human testis shows nuclear positivity in cells in seminiferous ducts and Leydig cells.

Applications for SAP18 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SAP18

Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter.

Alternate Names

2HOR0202cell growth inhibiting protein 38, Cell growth-inhibiting gene 38 protein, cell growth-inhibiting protein 38, histone deacetlyase complex subunit SAP18, histone deacetylase complex subunit SAP18,18 kDa Sin3-associated polypeptide, MGC27131, SAP18P, Sin3A-associated protein, 18kDa, Sin3-associated polypeptide p18, sin3-associated polypeptide, 18 kDa, sin3-associated polypeptide, p18

Gene Symbol

SAP18

Additional SAP18 Products

Product Documents for SAP18 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for SAP18 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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