SARM1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-77200

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human, Mouse

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all SARM1 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a peptide corresponding to 14 amino acids near the C-terminus of human SARM. The immunogen is located within amino acids 640 - 690 of SARM. Amino Acid Squence: EWPEPQALPEDMQA

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Porcine (86%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

85 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for SARM1 Antibody - BSA Free

Western Blot: SARM1 AntibodyBSA Free [NBP1-77200]

Western Blot: SARM1 AntibodyBSA Free [NBP1-77200]

Western Blot: SARM1 Antibody [NBP1-77200] - Analysis of SARM in Daudi cell lysate with SARM antibody at (A) 0.5 and (B) 1 ug/mL.
Immunocytochemistry/ Immunofluorescence: SARM1 Antibody - BSA Free [NBP1-77200]

Immunocytochemistry/ Immunofluorescence: SARM1 Antibody - BSA Free [NBP1-77200]

Immunocytochemistry/Immunofluorescence: SARM1 Antibody [NBP1-77200] - Analysis of SARM in formalin-fixed Daudi cells using NBP1-77200 at 2 ug/ml.
Immunocytochemistry/ Immunofluorescence: SARM1 Antibody - BSA Free [NBP1-77200]

Immunocytochemistry/ Immunofluorescence: SARM1 Antibody - BSA Free [NBP1-77200]

Immunocytochemistry/Immunofluorescence: SARM1 Antibody [NBP1-77200] - Daudi cells at 2ug/ml

Applications for SARM1 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

2 ug/ml

Western Blot

0.5-1 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SARM1

Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. SARM (SAM and ARM-containing protein), along with other molecules such as TIRP, TRIF, TIRAP, and MyD88, is thought to serve as an adaptor protein for the TLRs that allows for the activation of downstream kinases and NF-kappaB, and ultimately the expression of proteins involved in host defense. While SARM has not been conclusively shown to associate directly with TLRs, the presence of a Toll-interluekin-1 (TIR) domain in SARM is consistent with a role as a signaling molecule.

Long Name

Sterile alpha and TIR Motif Containing 1

Alternate Names

SAMD2

Gene Symbol

SARM1

UniProt

NP_055892 (Human)

Additional SARM1 Products

Product Documents for SARM1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for SARM1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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