SCN1B Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-10353

Novus Biologicals, part of Bio-Techne
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NBP3-10353-100ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

0.5 mg/ml

View all SCN1B Antibodies »

Product Summary for SCN1B Antibody

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human SCN1B (NP_001028). Peptide sequence NVTYNHSGDYECHVYRLLFFENYEHNTSVVKKIHIEVVDKANRDMASIVS

Clonality

Polyclonal

Host

Rabbit

Theoretical MW

25 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for SCN1B Antibody

Western Blot: SCN1B Antibody [NBP3-10353]

Western Blot: SCN1B Antibody [NBP3-10353]

Western Blot: SCN1B Antibody [NBP3-10353] - Western blot analysis using NBP3-10353 on Human HeLa as a positive control. Antibody Titration: 0.2-1 ug/ml

Applications for SCN1B Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SCN1B

Voltage-gated sodium channels are heteromeric proteins that function in the generation and propagation of action potentials in muscle and neuronal cells. They are composed of one alpha and two beta subunits, where the alpha subunit provides channel activity and the beta-1 subunit modulates the kinetics of channel inactivation. This gene encodes a sodium channel beta-1 subunit. Mutations in this gene result in generalized epilepsy with febrile seizures plus, Brugada syndrome 5, and defects in cardiac conduction. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternate Names

GEFSP1, sodium channel beta-1 subunit, sodium channel subunit beta-1, sodium channel, voltage-gated, type I, beta, sodium channel, voltage-gated, type I, beta polypeptide

Gene Symbol

SCN1B

Additional SCN1B Products

Product Documents for SCN1B Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SCN1B Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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