SCO1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-77273

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Validated:

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all SCO1 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 14 amino acid synthetic peptide from near the center of human SCO1. The immunogen is located within amino acids 100 - 150 of SCO1. Amino Acid Squence: HVKKEKAEKLEKER

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SCO1 Antibody - BSA Free

Western Blot: SCO1 AntibodyBSA Free [NBP1-77273]

Western Blot: SCO1 AntibodyBSA Free [NBP1-77273]

Western Blot: SCO1 Antibody [NBP1-77273] - Human brain tissue lysate with SCO1 antibody at (A) 0.5 and (B) 1 ug/mL.
Immunocytochemistry/ Immunofluorescence: SCO1 Antibody - BSA Free [NBP1-77273]

Immunocytochemistry/ Immunofluorescence: SCO1 Antibody - BSA Free [NBP1-77273]

Immunocytochemistry/Immunofluorescence: SCO1 Antibody [NBP1-77273] - Human Brain cells.
Immunohistochemistry-Paraffin: SCO1 Antibody - BSA Free [NBP1-77273]

Immunohistochemistry-Paraffin: SCO1 Antibody - BSA Free [NBP1-77273]

Immunohistochemistry-Paraffin: SCO1 Antibody [NBP1-77273] - Human brain tissue with SCO1 antibody at 2.5 ug/ml.
View 4 more images

Applications for SCO1 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Immunohistochemistry

2.5 ug/ml

Immunohistochemistry-Paraffin

2.5 ug/ml

Western Blot

0.5-1 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SCO1

Synthesis of cytochrome c oxidase 1 was initially identified in yeast as one of two cytochrome c oxidase (COX) assembly proteins that enable the assembly of cytochrome c holoenzyme, a complex that catalyzes the transfer of reducing equivalents from cytochrome c to molecular oxygen and pumps protons across the inner mitochondrial membrane. Like their yeast homologs, the function of both SCO1 and SCO2 are dependent on copper ion binding. Mutations in either gene can lead to cytochrome c oxidase respiratory chain defects, with a missense mutation in human SCO1 (P174L) associated with a fatal neonatal hepatopathy when the second allele is also non-functional, suggesting the pathology is due to loss of function. It has been suggested that this mutation alters the SCO1 affinity for the copper (I) ion, thus impairing the efficiency of copper transfer to the cytochrome c oxidase. At least two isoforms of SCO1 are known to exist and both are recognized by the SCO1 antibody. This SCO1 antibody has no cross-reactivity to SCO2.

Alternate Names

protein SCO1 homolog, mitochondrial, SCO cytochrome oxidase deficient homolog 1 (yeast), SCOD1SCO (cytochrome oxidase deficient, yeast) homolog 1

Gene Symbol

SCO1

UniProt

O75880 (Human)

Additional SCO1 Products

Product Documents for SCO1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for SCO1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.