Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Predicted:

Bovine (100%), Sheep (100%). Backed by our 100% Guarantee.

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all SDHD Antibodies »

Product Specifications

Immunogen

SDHD antibody was raised against a 15 amino acid synthetic peptide near the center of human SDHD. The immunogen is located within amino acids 30 - 80 of SDHD. Amino Acid Squence: HLSPSHHSGSKAASL

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Porcine: (80%)

Specificity

At least four isoforms of SDHD are known to exist; this antibody will detect the two longest isoforms.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SDHD Antibody - BSA Free

Western Blot: SDHD AntibodyBSA Free [NBP2-81948]

Western Blot: SDHD AntibodyBSA Free [NBP2-81948]

Western Blot: SDHD Antibody [NBP2-81948] - Analysis of SDHD in EL4 cell lysate with SDHD antibody at (A) 1 and (B) 2 ug/ml.
Immunocytochemistry/ Immunofluorescence: SDHD Antibody - BSA Free [NBP2-81948]

Immunocytochemistry/ Immunofluorescence: SDHD Antibody - BSA Free [NBP2-81948]

Immunocytochemistry/Immunofluorescence: SDHD Antibody [NBP2-81948] - Analysis of SDHD in EL4 cells with SDHD antibody at 2.5 ug/ml.
SDHD Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: SDHD Antibody - BSA Free [NBP2-81948] -

Immunocytochemistry/ Immunofluorescence: SDHD Antibody - BSA Free [NBP2-81948] - Immunofluorescence of SDHD in EL4 cells with SDHD antibody at 20 ug/mL.

Applications for SDHD Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

2.5 ug/ml

Western Blot

1-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SDHD

SDHD is part of Complex II. Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The subunit D protein is one of two integral membrane proteins anchoring the complex to the matrix side of the membrane. Mutations in SDHD have been linked to hereditary paraganglioma.

Alternate Names

CBT1, CII-4, cybS, PGL, PGL1, QPs3, SDH4, succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial, Succinate dehydrogenase complex subunit D, succinate dehydrogenase complex, subunit D, integral membrane protein, succinate dehydrogenase ubiquinone cytochrome B small subunit, Succinate-ubiquinone oxidoreductase cytochrome b small subunit, Succinate-ubiquinone reductase membrane anchor subunit

Gene Symbol

SDHD

Additional SDHD Products

Product Documents for SDHD Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for SDHD Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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