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SEC62 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-84045

Novus Biologicals, part of Bio-Techne
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NBP1-84045
NBP1-84045-25ul

Key Product Details

Species Reactivity

Validated:

Human, Canine

Cited:

Human, Canine

Predicted:

Mouse (91%), Rat (90%). Backed by our 100% Guarantee.

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: GGRHHFWFLPNLTADVGFIDSFRPLYTHEYKGPKADLKKDEKSETKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTDSDRREDDRSQHSSGNGNDFEMITKEELEQQTDGDCEEDEEEENDGETPKSS

Reactivity Notes

Canine reactivity reported in scientific literature (PMID: 26634806).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SEC62 Antibody

Western Blot: SEC62 Antibody [NBP1-84045]

Western Blot: SEC62 Antibody [NBP1-84045]

Western Blot: SEC62 Antibody [NBP1-84045] - Analysis in human cell line A-431.
Immunocytochemistry/ Immunofluorescence: SEC62 Antibody [NBP1-84045]

Immunocytochemistry/ Immunofluorescence: SEC62 Antibody [NBP1-84045]

Immunocytochemistry/Immunofluorescence: SEC62 Antibody [NBP1-84045] - Staining of human cell line A-431 shows positivity in endoplasmic reticulum. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: SEC62 Antibody [NBP1-84045]

Immunohistochemistry-Paraffin: SEC62 Antibody [NBP1-84045]

Immunohistochemistry-Paraffin: SEC62 Antibody [NBP1-84045] - Staining of human cerebral cortex shows strong cytoplasmic positivity in neurons.

Applications for SEC62 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SEC62

The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. (provided by RefSeq)

Alternate Names

Dtrp1, hTP-1, S.cerevisiae, homolog of, SEC62 homolog (S. cerevisiae), TLOC1, TP-1, translocation protein 1, translocation protein SEC62

Gene Symbol

SEC62

Additional SEC62 Products

Product Documents for SEC62 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SEC62 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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