Key Product Details

Validated by

Independent Antibodies, Biological Validation

Species Reactivity

Human

Applications

Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all SELS Antibodies »

Product Specifications

Immunogen

The immunogen this antibody was made to, maps to a region between residue 125 to 175 of human Selenoprotein S using the numbering given in entry NP_982298.1 (GeneID 55829).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SELS Antibody

Western Blot: SELS Antibody [NBP2-32096]

Western Blot: SELS Antibody [NBP2-32096]

Western Blot: SELS Antibody [NBP2-32096] - Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) prepared using NETN buffer from HeLa cells. Antibodies: Affinity purified rabbit anti-Selenoprotein S antibody NBP2-32096 used for IP at 6 ug per reaction. Selenoprotein S was also immunoprecipitated by rabbit anti-Selenoprotein S antibody BL16285. For blotting immunoprecipitated Selenoprotein S, NBP2-32096 was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.
Western Blot: SELS Antibody [NBP2-32096]

Western Blot: SELS Antibody [NBP2-32096]

Western Blot: SELS Antibody [NBP2-32096] - Whole cell lysate (50 ug) prepared using NETN or RIPA buffer from HeLa, 293T, and Jurkat cells. Antibodies: Affinity purified rabbit anti-Selenoprotein S antibody NBP2-32096 used for WB at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

Applications for SELS Antibody

Application
Recommended Usage

Immunoprecipitation

2 - 10 ug/mg lysate

Western Blot

1:1000 - 1:5000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: SELS

SELS encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Studies suggest that this protein may regulate cytokine production, and thus play a key role in the control of the inflammatory response. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.

Alternate Names

ADO15, MGC104346, SBBI8, selenoprotein S, SelS, SEPS1, VCP-interacting membrane protein, VIMPMGC2553

Gene Symbol

VIMP

UniProt

NP_982298.1 (Human)

Additional SELS Products

Product Documents for SELS Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SELS Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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