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Semaphorin 7A Antibody (MEM-150)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-09169

Clone MEM-150 was used by HLDA to establish CD designation.
Novus Biologicals, part of Bio-Techne
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NBP3-09169

Key Product Details

Species Reactivity

Validated:

Human

Applications

Flow Cytometry, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgM Clone # MEM-150

Concentration

1 mg/ml

Product Summary for Semaphorin 7A Antibody (MEM-150)

Immunogen

HPB-ALL human T cell line

Specificity

The antibody MEM-150 reacts with CD108 (JMH blood group antigen), a 80 kDa GPI-anchored extracellular glycoprotein expressed on various cell types including erythrocytes, lymphoblasts; at low levels it is present on circulating lymphocytes.

Clonality

Monoclonal

Host

Mouse

Isotype

IgM

Scientific Data Images for Semaphorin 7A Antibody (MEM-150)

Flow Cytometry: Semaphorin 7A Antibody (MEM-150) [NBP3-09169]

Flow Cytometry: Semaphorin 7A Antibody (MEM-150) [NBP3-09169]

Flow Cytometry: Semaphorin 7A Antibody (MEM-150) [NBP3-09169] - Analysis (surface staining) of human peripheral blood with anti-human CD108 (MEM-150) purified, GAM IgM PE.

Applications for Semaphorin 7A Antibody (MEM-150)

Application
Recommended Usage

Flow Cytometry

4 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Chromatography

Formulation

TBS

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Semaphorin 7A

required for central and peripheral axon growth and is required for proper axon tract formation during embryonic development. Semaphorin 7a is also involved in modulating immune function. Semaphorin 7a expression is highest in the brain and increases in late embryonic and postnatal stages. The Semaphorins constitute a large family of secreted and membrane-tethered cell signaling molecules. They have functions in neural development, immunology, cardiac growth, vascular development, lung morphogenesis and axial bone patterning. Semaphorins are defined by the presence of a conserved Sema domain at the N-terminus. These proteins can be classified into eight classes depending on their structure and species origin. Classes 3 through 7 are found in vertebrates; class 3 are secreted, class 7 are GPI-anchored, and class 4 through 6 are transmembrane proteins.

Alternate Names

CD108, H-Sema-L, Sema7A, SEMAL

Gene Symbol

SEMA7A

Additional Semaphorin 7A Products

Product Documents for Semaphorin 7A Antibody (MEM-150)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Semaphorin 7A Antibody (MEM-150)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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