Semaphorin 7A Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-86555

Novus Biologicals, part of Bio-Techne
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NBP1-86555
NBP1-86555-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Semaphorin 7A Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: QDRVDFGQTEPHTVLFHEPGSSSVWVGGRGKVYLFDFPEGKNASVRTVNIGSTKGSCLDKRDCENYITLLERRSEGLLACGTNARHPSCWNLVNGTVVPLGEMRGYAPFSPDENSLVLFEGD

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (85%), Rat (87%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Semaphorin 7A Antibody

Immunohistochemistry-Paraffin: Semaphorin 7A Antibody [NBP1-86555]

Immunohistochemistry-Paraffin: Semaphorin 7A Antibody [NBP1-86555]

Immunohistochemistry-Paraffin: Semaphorin 7A Antibody [NBP1-86555] - Staining of human placenta shows moderate to strong membranous positivity in trophoblastic cells.
Immunohistochemistry-Paraffin: Semaphorin 7A Antibody [NBP1-86555]

Immunohistochemistry-Paraffin: Semaphorin 7A Antibody [NBP1-86555]

Immunohistochemistry-Paraffin: Semaphorin 7A Antibody [NBP1-86555] - Staining in human testis and skeletal muscle tissues.. Corresponding SEMA7A RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: Semaphorin 7A Antibody [NBP1-86555]

Immunohistochemistry-Paraffin: Semaphorin 7A Antibody [NBP1-86555]

Immunohistochemistry-Paraffin: Semaphorin 7A Antibody [NBP1-86555] - Staining of human cerebral cortex shows moderate to strong membranous positivity in neurons.
View 2 more images

Applications for Semaphorin 7A Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Semaphorin 7A

required for central and peripheral axon growth and is required for proper axon tract formation during embryonic development. Semaphorin 7a is also involved in modulating immune function. Semaphorin 7a expression is highest in the brain and increases in late embryonic and postnatal stages. The Semaphorins constitute a large family of secreted and membrane-tethered cell signaling molecules. They have functions in neural development, immunology, cardiac growth, vascular development, lung morphogenesis and axial bone patterning. Semaphorins are defined by the presence of a conserved Sema domain at the N-terminus. These proteins can be classified into eight classes depending on their structure and species origin. Classes 3 through 7 are found in vertebrates; class 3 are secreted, class 7 are GPI-anchored, and class 4 through 6 are transmembrane proteins.

Alternate Names

CD108, H-Sema-L, Sema7A, SEMAL

Gene Symbol

SEMA7A

Additional Semaphorin 7A Products

Product Documents for Semaphorin 7A Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Semaphorin 7A Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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