SERCA1 ATPase Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-25129

Novus Biologicals, part of Bio-Techne
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NBP3-25129
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (96%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all SERCA1 ATPase Antibodies »

Product Specifications

Immunogen

This antibody has been engineered to specifically recognize the recombinant protein SERCA1 ATPase using the following amino acid sequence: NYVRVGTTRVPLTGPVKEKIMAVIK

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SERCA1 ATPase Antibody - BSA Free

SERCA1 ATPase Antibody Immunohistochemistry-Paraffin: SERCA1 ATPase Antibody [NBP3-25129]

Immunohistochemistry-Paraffin: SERCA1 ATPase Antibody [NBP3-25129]

Staining of human skeletal muscle shows strong cytoplasmic positivity in myocytes.

Applications for SERCA1 ATPase Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, we recommend using Heat-Induced Epitope Retrieval (HIER) with a pH level of 6. This optimized retrieval method ensures the best results for your experiments.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SERCA1 ATPase

SERCA1 ATPase encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in two transcript variants encoding different isoforms.

Long Name

Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

Alternate Names

ATP2A1, Calcium pump 1, EC 7.2.2.10, SERCA1, SR Ca(2+)-ATPase 1

Gene Symbol

ATP2A1

Additional SERCA1 ATPase Products

Product Documents for SERCA1 ATPase Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for SERCA1 ATPase Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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