Serine Palmitoyltransferase 2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-20308

Novus Biologicals, part of Bio-Techne
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NBP2-20308
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Key Product Details

Validated by

Biological Validation

Species Reactivity

Validated:

Human, Mouse

Predicted:

Bovine (95%), Rat (95%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Serine Palmitoyltransferase 2 Antibodies »

Product Summary for Serine Palmitoyltransferase 2 Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human Serine palmitoyltransferase 2. The exact sequence is proprietary.

Reactivity Notes

Chicken (84%), Xenopus laevis (80%).

Localization

Endoplasmic reticulum membrane; Single-pass membrane protein

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

63 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Serine Palmitoyltransferase 2 Antibody

Western Blot: Serine Palmitoyltransferase 2 Antibody [NBP2-20308]

Western Blot: Serine Palmitoyltransferase 2 Antibody [NBP2-20308]

Western Blot: Serine Palmitoyltransferase 2 Antibody [NBP2-20308] - Serine Palmitoyltransferase 2 levels in human neuroblastoma cells. Cells were untreated or treated with various drugs. Image from verified customer review.
Immunohistochemistry-Paraffin: Serine Palmitoyltransferase 2 Antibody [NBP2-20308]

Immunohistochemistry-Paraffin: Serine Palmitoyltransferase 2 Antibody [NBP2-20308]

Immunohistochemistry-Paraffin: Serine Palmitoyltransferase 2 Antibody [NBP2-20308] - Immunohistochemical analysis of paraffin-embedded Hepatoma, using antibody at 1:500 dilution.
Western Blot: Serine Palmitoyltransferase 2 Antibody [NBP2-20308]

Western Blot: Serine Palmitoyltransferase 2 Antibody [NBP2-20308]

Western Blot: Serine Palmitoyltransferase 2 Antibody [NBP2-20308] - Sample (30 ug of whole cell lysate) A: IMR32 7. 5% SDS PAGE gel, diluted at 1:1000.
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Applications for Serine Palmitoyltransferase 2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000
Application Notes
Serine Palmitoyltransferase 2 antibody validated for WB from a verified customer review.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol, 1% BSA

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Serine Palmitoyltransferase 2

This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. Alternatively spliced variants encoding different isoforms have been identified. [provided by RefSeq]

Long Name

Serine palmitoyltransferase 2

Alternate Names

EC 2.3.1.50, KIAA0526, LCB 2, LCB2, LCB2a, SPT 2, SPTLC2

Gene Symbol

SPTLC2

UniProt

O15270 (Human)

Additional Serine Palmitoyltransferase 2 Products

Product Documents for Serine Palmitoyltransferase 2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Serine Palmitoyltransferase 2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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