Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark. Do not freeze.

Background: Serpin A5/Protein C Inhibitor

PAI-1, PAI-2 and PAI-3 (plasminogen activator inhibitor-1, -2 and -3) are members of the serpin serine proteinase inhibitor family. PAI-1 and PAI-2 regulate uPA (urokinase-type plasminogen activator) and TPA (tissue plasminogen activator), resulting in the inhibition of proteolytic activity. Members of the serpin family generally complex with their target proteinases, then disassociate slowly into cleaved species that fold into stable inactive forms. PAI-1 can fold into the inactive state without cleavage resulting in the latent form of PAI-1. Activity can be restored to the latent form of PAI-1 through denaturation and renaturation. PAI-2 occurs in secreted and cytosolic forms through facultative polypeptide translocation. PAI-3 inhibits plasminogen activators as well as activated protein C. PAI-3 is secreted in plasma, but is also expressed in liver.

Alternate Names

PAI-3, PCI

Gene Symbol

SERPINA5

Additional Serpin A5/Protein C Inhibitor Products

Product Documents for Serpin A5/Protein C Inhibitor Antibody (OTI1C4) [PE/Atto594]

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices for Serpin A5/Protein C Inhibitor Antibody (OTI1C4) [PE/Atto594]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations
Reviews

Spectra Viewer
Flow Cytometry

Serpin A5/Protein C Inhibitor Antibody (OTI1C4) [PE/Atto594]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-74100PEATT594

Key Product Details

Species Reactivity

Validated:

Applications

Label

Antibody Source

Concentration

View all Serpin A5/Protein C Inhibitor Antibodies »

Product Summary for Serpin A5/Protein C Inhibitor Antibody (OTI1C4) [PE/Atto594]

Immunogen

Clonality

Host

Isotype

Applications for Serpin A5/Protein C Inhibitor Antibody (OTI1C4) [PE/Atto594]

Flow Cytometry

Western Blot

Formulation, Preparation, and Storage

Purification

Formulation

Preservative

Concentration

Shipping

Stability & Storage

Background: Serpin A5/Protein C Inhibitor

Alternate Names

Gene Symbol

Additional Serpin A5/Protein C Inhibitor Products

Product Documents for Serpin A5/Protein C Inhibitor Antibody (OTI1C4) [PE/Atto594]

Product Datasheets

COA

Certificate of Analysis

SDS

Product Specific Notices for Serpin A5/Protein C Inhibitor Antibody (OTI1C4) [PE/Atto594]

CONTACT INFORMATION

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