Serpin A8/Angiotensinogen Antibody (8A9)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-26518

Recombinant monoclonal antibody expressed in HEK293F cells
Novus Biologicals, part of Bio-Techne
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NBP3-26518-100ul
NBP3-26518-50ul
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunohistochemistry

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 8A9

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Serpin A8/Angiotensinogen Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from Human Serpin A8/Angiotensinogen [UniProt P01019]

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Serpin A8/Angiotensinogen Antibody (8A9)

Serpin A8/Angiotensinogen Antibody (8A9)

Immunohistochemistry: Serpin A8/Angiotensinogen Antibody (8A9) [NBP3-26518] -

Immunohistochemistry: Serpin A8/Angiotensinogen Antibody (8A9) [NBP3-26518] - Image of Serpin A8/Angiotensinogen Antibody (8A9) diluted at 1:100 and staining in paraffin-embedded human kidney tissue performed. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

Applications for Serpin A8/Angiotensinogen Antibody (8A9)

Application
Recommended Usage

Immunohistochemistry

1:50-1:200

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl and 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 to -70C. Avoid freeze-thaw cycles.

Background: Serpin A8/Angiotensinogen

Angiotensin II is encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.

Alternate Names

AGT, Angiotensin II, Angiotensinogen, Aogen, PAT

Gene Symbol

AGT

Additional Serpin A8/Angiotensinogen Products

Product Documents for Serpin A8/Angiotensinogen Antibody (8A9)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Serpin A8/Angiotensinogen Antibody (8A9)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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