Serpin A8/Angiotensinogen Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-99680

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Serpin A8/Angiotensinogen Antibodies »

Product Specifications

Immunogen

Produced in rabbits immunized with purified, recombinant Human Serpin A8/Angiotensinogen (Accession#: NP_000020.1; Met 1-Ala 485)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C to 8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for Serpin A8/Angiotensinogen Antibody

Immunohistochemistry-Paraffin: Serpin A8/Angiotensinogen Antibody [NBP2-99680]

Immunohistochemistry-Paraffin: Serpin A8/Angiotensinogen Antibody [NBP2-99680]

Immunohistochemistry-Paraffin: Serpin A8/Angiotensinogen Antibody [NBP2-99680] - Immunochemical staining of human Serpin A8/Angiotensinogen in human cirrhosis with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).The left panel: tissue incubated with primary antibody;The right panel: tissue incubated with the mixture of primary antibody and antigen (recombinant protein).

Applications for Serpin A8/Angiotensinogen Antibody

Application
Recommended Usage

ELISA

1:1000-1:2000

Immunohistochemistry-Paraffin

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Serpin A8/Angiotensinogen

Angiotensin II is encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.

Alternate Names

AGT, Angiotensin II, Angiotensinogen, Aogen, PAT

Gene Symbol

AGT

Additional Serpin A8/Angiotensinogen Products

Product Documents for Serpin A8/Angiotensinogen Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Serpin A8/Angiotensinogen Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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