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Serpin C1/Antithrombin-III Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-15414

Novus Biologicals, part of Bio-Techne
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NBP2-15414

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Rhesus Macaque (91%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for Serpin C1/Antithrombin-III Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human Serpin C1/Antithrombin-III. The exact sequence is proprietary.

Reactivity Notes

Mouse (88%), Rat (86%), Pig (87%), Sheep (86%), Bovine (84%), Guinea pig (85%).

Localization

Secreted; extracellular space

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

53 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Serpin C1/Antithrombin-III Antibody

Immunocytochemistry/ Immunofluorescence: Serpin C1/Antithrombin-III Antibody [NBP2-15414]

Immunocytochemistry/ Immunofluorescence: Serpin C1/Antithrombin-III Antibody [NBP2-15414]

Immunocytochemistry/Immunofluorescence: Serpin C1/Antithrombin-III Antibody [NBP2-15414] - Analysis of methanol-fixed HeLa, using antibody at 1:500 dilution.
Immunohistochemistry-Paraffin: Serpin C1/Antithrombin-III Antibody [NBP2-15414]

Immunohistochemistry-Paraffin: Serpin C1/Antithrombin-III Antibody [NBP2-15414]

Immunohistochemistry-Paraffin: Serpin C1/Antithrombin-III Antibody [NBP2-15414] - Paraffin-embedded human lung adenocarcinoma. Antithrombin III antibody diluted at 1:250.
Serpin C1/Antithrombin-III Antibody

Western Blot: Serpin C1/Antithrombin-III Antibody [NBP2-15414] -

Western Blot: Serpin C1/Antithrombin-III Antibody [NBP2-15414] -Human plasma (30 ug) was separated by 12% SDS-PAGE, and the membrane was blotted with Antithrombin III antibody diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.

Applications for Serpin C1/Antithrombin-III Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol, 1% BSA

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Serpin C1/Antithrombin-III

The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency. [provided by RefSeq]

Alternate Names

Antithrombin-III, ATIII

Gene Symbol

SERPINC1

UniProt

Additional Serpin C1/Antithrombin-III Products

Product Documents for Serpin C1/Antithrombin-III Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Serpin C1/Antithrombin-III Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.