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SESN3 Antibody (2C9)

Novus Biologicals, part of Bio-Techne | Catalog # H00143686-M02

Novus Biologicals, part of Bio-Techne
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H00143686-M02

Key Product Details

Species Reactivity

Human, Mouse

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 2C9

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

SESN3 (AAH17296, 212 a.a. ~ 321 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. INPERDPEISNGFRLISVNNFCVCDLANDNNIENASLSGSNFGIVDSLSELEALMERMKRLQEEREDEEASQEEMSTRFEKEKKESLFVVSGDTFHSFPHSGAFLHFFAF

Reactivity Notes

Human. Other species not tested.

Specificity

SESN3 (2C9)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for SESN3 Antibody (2C9)

Western Blot: SESN3 Antibody (2C9) [H00143686-M02]

Western Blot: SESN3 Antibody (2C9) [H00143686-M02]

Western Blot: SESN3 Antibody (2C9) [H00143686-M02] - SESN3 monoclonal antibody (M02), clone 2C9. Analysis of SESN3 expression in human pancreas.

Applications for SESN3 Antibody (2C9)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody Reactive against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: SESN3

Sestrin 3 (SESN3) is a member of the sestrin family of proteins, which modulate peroxide signaling and antioxident defense. p53, a tumor suppressor, regulates the expression of proteins in this family. SESN3 is a promising target for selectively killing cancer cells containing high levels of AKT, a protein kinase that is hyperactivated in cancer cells. AKT is involved in cell proliferation and protects cells from apoptosis.

Alternate Names

SEST3MGC29667, sestrin 3, sestrin-3

Entrez Gene IDs

143686 (Human)

Gene Symbol

SESN3

OMIM

607768 (Human)

Additional SESN3 Products

Product Documents for SESN3 Antibody (2C9)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SESN3 Antibody (2C9)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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