SET1B Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-87896

Novus Biologicals, part of Bio-Techne
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NBP1-87896
NBP1-87896-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all SET1B Antibodies »

Product Summary for SET1B Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: DSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPER

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SET1B Antibody

Immunocytochemistry/ Immunofluorescence: SET1B Antibody [NBP1-87896]

Immunocytochemistry/ Immunofluorescence: SET1B Antibody [NBP1-87896]

Immunocytochemistry/Immunofluorescence: SET1B Antibody [NBP1-87896] - Staining of human cell line A-431 shows localization to nucleoplasm.
Immunohistochemistry-Paraffin: SET1B Antibody [NBP1-87896]

Immunohistochemistry-Paraffin: SET1B Antibody [NBP1-87896]

Immunohistochemistry-Paraffin: SET1B Antibody [NBP1-87896] - Staining of human urinary bladder shows strong nuclear positivity.

Applications for SET1B Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SET1B

hSET1B is a histone methyltransferase that associates in a complex with the non-catalytic subunits CFP1, Rbbp5, Ash2, Wdr5, and Wdr82. These five non-catalytic subunits are also part of the Set1A complex. The SET1B complex has been shown to catalyze the tri-methylation of 'Lys-4' on histone H3. SET1B has been shown to localize to sites independent of SET1A complexes indicating non-redundant functions between SET1B and SET1A complexes. hSET1B include SET domain-containing protein 1B, lysine N-methyltransferase 2G, SETD1B, KMT2G, SET1B, and KIAA1076.

Alternate Names

EC 2.1.1, FLJ20803, histone-lysine N-methyltransferase SETD1B, hSET1B, KIAA1076EC 2.1.1.43, KMT2GSET1B, Lysine N-methyltransferase 2G, SET domain containing 1B, SET domain-containing protein 1B, Set1B

Gene Symbol

SETD1B

Additional SET1B Products

Product Documents for SET1B Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for SET1B Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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