SETDB2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-31264

Novus Biologicals, part of Bio-Techne
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NBP1-31264
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (92%), Mouse (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all SETDB2 Antibodies »

Product Summary for SETDB2 Antibody

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human SETDB2. The exact sequence is proprietary.

Localization

Nucleus

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

82 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for SETDB2 Antibody

Immunocytochemistry/ Immunofluorescence: SETDB2 Antibody [NBP1-31264]

Immunocytochemistry/ Immunofluorescence: SETDB2 Antibody [NBP1-31264]

Immunocytochemistry/Immunofluorescence: SETDB2 Antibody [NBP1-31264] - Sample: HCT 116 cells were fixed in 4% paraformaldehyde at RT for 15 min.Green: SETDB2 protein stained by SETDB2 antibody [N1], N-term diluted at 1:2000. Blue: Hoechst 33342 staining.

Applications for SETDB2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: SETDB2

Proteins that contain a SET domain, such as SETDB2, modulate gene expression epigenetically through histone H3 (see MIM 601128) methylation. SETDB2 is likely a histone H3 methyltransferase, as it contains both the active site and flanking cysteine residues required for catalytic activity (Zhang et al., 2003 [PubMed 12754510]).[supplied by OMIM]

Alternate Names

C13orf4, chromosome 13 open reading frame 4, chronic lymphocytic leukemia deletion region 8, Chronic lymphocytic leukemia deletion region gene 8 protein, CLLD8DKFZp761J1217, DKFZp586I0123, EC 2.1.1.43, histone-lysine N-methyltransferase SETDB2, KMT1FCLLL8, Lysine N-methyltransferase 1F, SET domain bifurcated 2, SET domain, bifurcated 2

Entrez Gene IDs

83852 (Human)

Gene Symbol

SETDB2

UniProt

Q96T68 (Human)

Additional SETDB2 Products

Product Documents for SETDB2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for SETDB2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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