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SH3BP2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-58872

Novus Biologicals, part of Bio-Techne
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NBP1-58872

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

Product Specifications

Immunogen

Synthetic peptides corresponding to SH3BP2(SH3-domain binding protein 2) The peptide sequence was selected from the middle region of SH3BP2. Peptide sequence RQPSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEPQ. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for SH3BP2 Antibody

Western Blot: SH3BP2 Antibody [NBP1-58872]

Western Blot: SH3BP2 Antibody [NBP1-58872]

Western Blot: SH3BP2 Antibody [NBP1-58872] - Titration: 1 ug/ml Positive Control: 721_B cell lysate.
Immunohistochemistry: SH3BP2 Antibody [NBP1-58872]

Immunohistochemistry: SH3BP2 Antibody [NBP1-58872]

Immunohistochemistry: SH3BP2 Antibody [NBP1-58872] - Staining of human liver cross section.
Immunohistochemistry-Paraffin: SH3BP2 Antibody [NBP1-58872]

Immunohistochemistry-Paraffin: SH3BP2 Antibody [NBP1-58872]

Immunohistochemistry-Paraffin: SH3BP2 Antibody [NBP1-58872] - Human kidney Tissue, antibody concentration 5 ug/ml.

Applications for SH3BP2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SH3BP2

SH3BP2 has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases, and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism.

Alternate Names

Abl-SH3 binding protein 2, Cherubism, CRBM, CRPM, FLJ42079, FLJ54978,3BP-2,3BP2, RES4-23, SH3 domain-binding protein 2, SH3-domain binding protein 2, TNFAIP3 interacting protein 2

Gene Symbol

SH3BP2

UniProt

Additional SH3BP2 Products

Product Documents for SH3BP2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SH3BP2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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