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SHANK1 Antibody [DyLight 350]

Novus Biologicals, part of Bio-Techne | Catalog # NB300-166UV

Novus Biologicals, part of Bio-Techne
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NB300-166UV

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Western Blot

Label

DyLight 350 (Excitation = 353 nm, Emission = 432 nm)

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for SHANK1 Antibody [DyLight 350]

Immunogen

A synthetic peptide made to an N terminal portion of human SHANK1 protein (between residues 110-160) [UniProt Q9Y566]

Reactivity Notes

Reacts with human and rat Shank1a. Does not react with mouse Shank1a.

Localization

Cytoplasmic, Cell junction, Postsynaptic density of neuronal cells.

Specificity

Reacts with residues [ERLLREYPQSFEKGV] of the N terminus of the rat Shank1a protein.

Marker

TGN Marker

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for SHANK1 Antibody [DyLight 350]

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: SHANK1

Shank is a novel family of postsynaptic density proteins (PSD) that bind to PSD-95-associated protein GKAP. Its putative function is to act as a scaffold protein in the PSD to cross-link NMDA receptors/PSD-95 complexes and couple them to regulators of the actin cytoskeleton. Shank1a is a splice variant of Shank1.

Alternate Names

SH3 and multiple ankyrin repeat domains 1, SH3 and multiple ankyrin repeat domains protein 1, Shank1, Somatostatin receptor-interacting protein, SSTR-interacting protein, SSTRIPSPANK-1, synamon

Gene Symbol

SHANK1

Additional SHANK1 Products

Product Documents for SHANK1 Antibody [DyLight 350]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SHANK1 Antibody [DyLight 350]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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