SHMT1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21429

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all SHMT1 Antibodies »

Product Specifications

Immunogen

Produced in rabbits immunized with E. coli-derived Human SHMT1 fragment

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C.

Scientific Data Images for SHMT1 Antibody

SHMT1 Antibody Immunohistochemistry-Paraffin: SHMT1 Antibody [NBP3-21429]

Immunohistochemistry-Paraffin: SHMT1 Antibody [NBP3-21429]

Immunochemical staining of SHMT1 in human kidney formalin-fixed paraffin embedded sections with NBP3-21429 at 1:100 dilution
SHMT1 Antibody Immunohistochemistry-Paraffin: SHMT1 Antibody [NBP3-21429]

Immunohistochemistry-Paraffin: SHMT1 Antibody [NBP3-21429]

Immunochemical staining of SHMT1 in human liver formalin-fixed paraffin embedded sections with NBP3-21429 at 1:100 dilution

Applications for SHMT1 Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:50-1:200

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

PBS, pH 7.0

Preservative

0.03% Proclin 300

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SHMT1

SHMT1 encodes the cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing of this gene results in 2 transcript variants encoding 2 different isoforms. Additional transcript variants have been described, but their biological validity has not been determined.

Long Name

Serine hydroxymethyltransferase, cytosolic

Alternate Names

EC 2.1.2.1, Serine methylase, SHMT

Gene Symbol

SHMT1

Additional SHMT1 Products

Product Documents for SHMT1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SHMT1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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