SIGIRR Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-56890

Novus Biologicals, part of Bio-Techne
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NB100-56890
NB100-56890SS
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all SIGIRR Antibodies »

Product Summary for SIGIRR Antibody

Immunogen

This antibody was developed against a synthetic peptide corresponding to amino acids 334-358 of human SIGIRIR.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SIGIRR Antibody

Western Blot: SIGIRR Antibody [NB100-56890]

Western Blot: SIGIRR Antibody [NB100-56890]

Western Blot: SIGIRR Antibody [NB100-56890] - Analysis of human SIGIRR in 15 ugs of (A) human kidney and (B) mouse kidney cell lysate using this antibody at 0.5 ug/ml.

Applications for SIGIRR Antibody

Application
Recommended Usage

Western Blot

0.5-1 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SIGIRR

The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules (1). TIR8, also know as single Ig IL-1 receptor, is a member of the IL-1/TLR superfamily (2). TIR8 acts as intracellular decoy to inhibit NF-kappaB activation by members of the IL-1/TLR family (3, 4).

Long Name

Single lg IL-1 Related Protein

Alternate Names

IL-1R8, TIR8

Entrez Gene IDs

59307 (Human); 24058 (Mouse)

Gene Symbol

SIGIRR

UniProt

Q6IA17

Additional SIGIRR Products

Product Documents for SIGIRR Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for SIGIRR Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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