Siglec-9 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-27070

Novus Biologicals, part of Bio-Techne
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NBP2-27070
NBP2-27070SS
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Key Product Details

Species Reactivity

Validated:

Bovine, Canine, Equine, Monkey, Primate

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all Siglec-9 Antibodies »

Product Summary for Siglec-9 Antibody

Immunogen

A portion of amino acids 40-90 of human Siglec9 was used as the immunogen.

Reactivity Notes

The amino acid sequence used as immunogen is 100% homologous in dwarf chimpanzee.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Siglec-9 Antibody

Western Blot: Siglec-9 Antibody [NBP2-27070]

Western Blot: Siglec-9 Antibody [NBP2-27070]

Western Blot: Siglec-9 Antibody [NBP2-27070] - Analysis using Siglec-9 antibody. Lysate from human liver in the 1) absence and 2) presence of immunizing peptide, 3) mouse and 4) rat liver. Goat anti-rabbit IgG HRP secondary antibody and PicoTect ECL substrate solution were used for this test.

Applications for Siglec-9 Antibody

Application
Recommended Usage

Western Blot

2-4ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.2 ml PBS and 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Siglec-9

Siglec9 (Sialic acid-binding Ig-like lectin 9) is single-pass type I membrane protein and belongs to immunoglobulin super family and contains two Ig-like C2 type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. It is reported that Siglec9 recognizes sialic acid in alpha2, 3-or alpha2, 6-glycosidic linkage to galactose. Using a specific antibody, Siglec9 was found to be expressed at high or intermediate levels by monocytes, neutrophils, and a minor population of CD16+, CD56- cells. Siglec9 also acts as an inhibitory receptor for MUC16 that attenuates T- and Nk cell function. Recent reports suggest that Siglec9 expressed on DCs is involved in immuno regulation through ligation with mucins in an epithelial cancer patient.

Long Name

Sialic Acid Binding Ig-like Lectin 9

Alternate Names

CD329, OBBP-Like, Siglec9

Gene Symbol

SIGLEC9

UniProt

Q9Y336

Additional Siglec-9 Products

Product Documents for Siglec-9 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Siglec-9 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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