Sigma-1 R/OPRS1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-82480

Novus Biologicals, part of Bio-Techne
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NBP1-82480
NBP1-82480-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (94%), Rat (96%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Sigma-1 R Antibodies »

Product Summary for Sigma-1 R/OPRS1 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: HSGRYWAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTY

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Sigma-1 R/OPRS1 Antibody

Immunohistochemistry-Paraffin: Sigma-1 R/OPRS1 Antibody [NBP1-82480]

Immunohistochemistry-Paraffin: Sigma-1 R/OPRS1 Antibody [NBP1-82480]

Immunohistochemistry-Paraffin: Sigma-1 R/OPRS1 Antibody [NBP1-82480] - Staining of human placenta shows strong cytoplasmic positivity in trophoblastic cells.
Immunohistochemistry-Paraffin: Sigma-1 R/OPRS1 Antibody [NBP1-82480]

Immunohistochemistry-Paraffin: Sigma-1 R/OPRS1 Antibody [NBP1-82480]

Immunohistochemistry-Paraffin: Sigma-1 R/OPRS1 Antibody [NBP1-82480] - Staining of human liver shows strong cytoplasmic positivity in hepatocytes.
Immunohistochemistry-Paraffin: Sigma-1 R/OPRS1 Antibody [NBP1-82480]

Immunohistochemistry-Paraffin: Sigma-1 R/OPRS1 Antibody [NBP1-82480]

Immunohistochemistry-Paraffin: Sigma-1 R/OPRS1 Antibody [NBP1-82480] - Analysis in human liver and skeletal muscle tissues using NBP1-82480 antibody. Corresponding SIGMAR1 RNA-seq data are presented for the same tissues.
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Applications for Sigma-1 R/OPRS1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Sigma-1 R

OPRS1 encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Alternative splicing of this gene results in transcript variants encoding distinct isoforms. [provided by RefSeq]. Transcript Variant: This variant (1) encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Long Name

Sigma Non-opioid Intracellular Receptor 1

Alternate Names

ALS16, OPRS1, SIG-1R, Sigma-1R, Sigma1R, SIGMAR1, SRBP

Gene Symbol

SIGMAR1

Additional Sigma-1 R Products

Product Documents for Sigma-1 R/OPRS1 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Sigma-1 R/OPRS1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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