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Sigma-1 R/OPRS1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-47257

Novus Biologicals, part of Bio-Techne
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NBP2-47257

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

LYOPH mg/ml

Product Summary for Sigma-1 R/OPRS1 Antibody

Immunogen

Synthetic peptide derived from an internal domain of human SIG-1R.

Specificity

Reacts with a 25 kDa protein. Predicted to cross react with SIG-1R of mouse and rat.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Store reconstituted liquid at 4C. For extended periods, aliquot and store at -20C. Avoid freeze-thaw cycles.

Applications for Sigma-1 R/OPRS1 Antibody

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry

1:100-1:2000

Western Blot

1:200-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Reconstitution

Lyophilized powder, reconstituted in distilled water.

Formulation

Lyophilized from 0.1M Tris, 0.1 glycine, 2% sucrose

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 °C.

Background: Sigma-1 R

OPRS1 encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Alternative splicing of this gene results in transcript variants encoding distinct isoforms. [provided by RefSeq]. Transcript Variant: This variant (1) encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Long Name

Sigma Non-opioid Intracellular Receptor 1

Alternate Names

ALS16, OPRS1, SIG-1R, Sigma-1R, Sigma1R, SIGMAR1, SRBP

Entrez Gene IDs

10280 (Human)

Gene Symbol

SIGMAR1

UniProt

Additional Sigma-1 R Products

Product Documents for Sigma-1 R/OPRS1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Sigma-1 R/OPRS1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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