Signal sequence receptor delta Antibody (2D3)

Novus Biologicals, part of Bio-Techne | Catalog # H00006748-M01

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 2D3

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Signal sequence receptor delta Antibodies »

Product Specifications

Immunogen

SSR4 (AAH03371, 24 a.a. ~ 173 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. EACLEPQITPSYYTTSDAVISTETVLIVEISLTCKNRVQNMALYADVGGKQFPVTRGQDVGRYQVSWSLDHKSAHAGTYEVRFFDEESYSLLRKAQRNNEDISIIPPLFTVSVDHRGTWNGPWVSTEVLAAAIGLVIYYLAFSAKSHIQA

Localization

Endoplasmic reticulum

Specificity

SSR4 - signal sequence receptor, delta (translocon-associated protein delta)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for Signal sequence receptor delta Antibody (2D3)

Western Blot: Signal sequence receptor delta Antibody (2D3) [H00006748-M01]

Western Blot: Signal sequence receptor delta Antibody (2D3) [H00006748-M01]

Western Blot: Signal sequence receptor delta Antibody (2D3) [H00006748-M01] - SSR4 monoclonal antibody (M01), clone 2D3 Analysis of SSR4 expression in C32.
Immunocytochemistry/ Immunofluorescence: Signal sequence receptor delta Antibody (2D3) [H00006748-M01]

Immunocytochemistry/ Immunofluorescence: Signal sequence receptor delta Antibody (2D3) [H00006748-M01]

Immunocytochemistry/Immunofluorescence: Signal sequence receptor delta Antibody (2D3) [H00006748-M01] - Analysis of monoclonal antibody to SSR4 on HeLa cell. Antibody concentration 10 ug/ml.
Western Blot: Signal sequence receptor delta Antibody (2D3) [H00006748-M01]

Western Blot: Signal sequence receptor delta Antibody (2D3) [H00006748-M01]

Western Blot: Signal sequence receptor delta Antibody (2D3) [H00006748-M01] - Analysis of SSR4 expression in transfected 293T cell line by SSR4 monoclonal antibody (M01), clone 2D3.Lane 1: SSR4 transfected lysate(19 KDa).Lane 2: Non-transfected lysate.
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Applications for Signal sequence receptor delta Antibody (2D3)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Sandwich ELISA

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for IF and ELISA.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Signal sequence receptor delta

SSR4, also called TRAPD, is assumed to be involved in protein secretion. It is located in the Xq28 region, arranged in a compact head-to-head manner with the IDH3G gene. These two genes are driven by a bidirectional promoter located between them, and encode proteins involved in unrelated biochemical pathways located in different compartments of the cell. The nontranscribed intergenic region represents only 133 bp and is embedded in a CpG island. The CpG island functions as a bidirectional promoter to initiate the transcription of both functionally unrelated genes with distinct expression patterns. SSR4 consists of six exons and is approximately 70 kb telomeric to the ALD gene. Although alternative splicing of exon 5 has not been detected in human SSR4, transcript variants missing the region homologous to human exon 5 have been detected in both Xenopus laevis and Mus musculus.

Alternate Names

signal sequence receptor, delta (translocon-associated protein delta), SSR-delta, translocon-associated protein delta, translocon-associated protein subunit delta, TRAP-delta, TRAPDSignal sequence receptor subunit delta

Entrez Gene IDs

6748 (Human)

Gene Symbol

SSR4

OMIM

300090 (Human)

UniProt

AAH03371 (Human)

Additional Signal sequence receptor delta Products

Product Documents for Signal sequence receptor delta Antibody (2D3)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Signal sequence receptor delta Antibody (2D3)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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