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Signal sequence receptor delta Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-92390

Novus Biologicals, part of Bio-Techne
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NBP1-92390

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Cited:

Human

Predicted:

Mouse (98%), Rat (98%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: TPSYYTTSDAVISTETVFIVEISLTCKNRVQNMALYADVGGKQFPVTRGQDVGRYQVSWSLDHKSAHAGTYEVRFFDEESYSLLRKAQRNNEDISIIPPLFTVSVDHRGTWNGPWVSTEVLAA

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Signal sequence receptor delta Antibody

Immunohistochemistry-Paraffin: Signal sequence receptor delta Antibody [NBP1-92390]

Immunohistochemistry-Paraffin: Signal sequence receptor delta Antibody [NBP1-92390]

Immunohistochemistry-Paraffin: Signal sequence receptor delta Antibody [NBP1-92390] - Analysis in human pancreas and skeletal muscle tissues using NBP1-92390 antibody. Corresponding SSR4 RNA-seq data are presented for the same tissues.
Western Blot: Signal sequence receptor delta Antibody [NBP1-92390]

Western Blot: Signal sequence receptor delta Antibody [NBP1-92390]

Western Blot: Signal sequence receptor delta Antibody [NBP1-92390] - Analysis in human cell line AN3-CA.
Immunohistochemistry-Paraffin: Signal sequence receptor delta Antibody [NBP1-92390]

Immunohistochemistry-Paraffin: Signal sequence receptor delta Antibody [NBP1-92390]

Immunohistochemistry-Paraffin: Signal sequence receptor delta Antibody [NBP1-92390] - Staining of human skeletal muscle shows no positivity in myocytes as expected.

Applications for Signal sequence receptor delta Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 -1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Reviewed Applications

Read 1 review rated 4 using NBP1-92390 in the following applications:

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Signal sequence receptor delta

SSR4, also called TRAPD, is assumed to be involved in protein secretion. It is located in the Xq28 region, arranged in a compact head-to-head manner with the IDH3G gene. These two genes are driven by a bidirectional promoter located between them, and encode proteins involved in unrelated biochemical pathways located in different compartments of the cell. The nontranscribed intergenic region represents only 133 bp and is embedded in a CpG island. The CpG island functions as a bidirectional promoter to initiate the transcription of both functionally unrelated genes with distinct expression patterns. SSR4 consists of six exons and is approximately 70 kb telomeric to the ALD gene. Although alternative splicing of exon 5 has not been detected in human SSR4, transcript variants missing the region homologous to human exon 5 have been detected in both Xenopus laevis and Mus musculus.

Alternate Names

signal sequence receptor, delta (translocon-associated protein delta), SSR-delta, translocon-associated protein delta, translocon-associated protein subunit delta, TRAP-delta, TRAPDSignal sequence receptor subunit delta

Gene Symbol

SSR4

Additional Signal sequence receptor delta Products

Product Documents for Signal sequence receptor delta Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Signal sequence receptor delta Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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