Sin1/MAPKAP1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-24523

Novus Biologicals, part of Bio-Techne
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NBP2-24523
NBP2-24523SS
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat, Bovine, Canine

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all Sin1/MAPKAP1 Antibodies »

Product Summary for Sin1/MAPKAP1 Antibody

Immunogen

A portion of amino acids 100-150 of human SIN1 was used as the immunogen for this antibody.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: xenopus (86%), chicken (86%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Sin1/MAPKAP1 Antibody

Western Blot: Sin1/MAPKAP1 Antibody [NBP2-24523]

Western Blot: Sin1/MAPKAP1 Antibody [NBP2-24523]

Western Blot: Sin1/MAPKAP1 Antibody [NBP2-24523] - Analysis of SIN1 in human skeletal muscle lysate in the 1) absence and 2) presence of immunizing peptide, 3) mouse skeletal muscle lysate and 4) rat skeletal muscle lysate using SIN1 at 2 ug/ml.
Immunohistochemistry-Paraffin: Sin1/MAPKAP1 Antibody [NBP2-24523]

Immunohistochemistry-Paraffin: Sin1/MAPKAP1 Antibody [NBP2-24523]

Immunohistochemistry-Paraffin: Sin1/MAPKAP1 Antibody [NBP2-24523] - Analysis of Transportin 1 in human liver tissue using Transportin 1 antibody at 10 ug/ml.

Applications for Sin1/MAPKAP1 Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

10 ug/ml

Western Blot

1-3 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

0.2 ml PBS and 0.2% Gelatin

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Sin1/MAPKAP1

Sin1 is a novel component of the eukaryotic SAPK pathway. Sin1 and the H3 and H4 histones interact genetically, with the C terminus of Sin1 physically associating with components of the SWI-SNF complex. This interaction is blocked by the N-terminal half of the protein in full length Sin1. It has been proposed that Sin1 acts as a regulatable bridge between the SWI-SNF complex and the nucleosome Sin1 is also required for effective transcription via the AP-1 factor Pap1, but does not prevent its nuclear translocation. Sin1 is a novel component of the eukaryotic SAPK pathway.

Long Name

Mitogen-Activated Protein Kinase Associated Protein 1

Alternate Names

JC310, MAPKAP1, MIP1

Gene Symbol

MAPKAP1

UniProt

Q92973 (Human)

Additional Sin1/MAPKAP1 Products

Product Documents for Sin1/MAPKAP1 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Sin1/MAPKAP1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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