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SIPA1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-20369

Novus Biologicals, part of Bio-Techne
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NBP2-20369

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Rat (92%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human SIPA1. The exact sequence is proprietary.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

112 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for SIPA1 Antibody

Western Blot: SIPA1 Antibody [NBP2-20369]

Western Blot: SIPA1 Antibody [NBP2-20369]

Western Blot: SIPA1 Antibody [NBP2-20369] - Western Blot analysis of SIPA1 expression in transfected 293T cell line by SIPA1 polyclonal antibody. A: Non-transfected lysate. B: SIPA1 transfected lysate. 7. 5% SDS PAGE gel, diluted at 1:500.
Immunocytochemistry/ Immunofluorescence: SIPA1 Antibody [NBP2-20369]

Immunocytochemistry/ Immunofluorescence: SIPA1 Antibody [NBP2-20369]

Immunocytochemistry/Immunofluorescence: SIPA1 Antibody [NBP2-20369] - Analysis of methanol-fixed mouse ESC, using SIPA1 antibody at 1:200 dilution.
Immunohistochemistry-Paraffin: SIPA1 Antibody [NBP2-20369]

Immunohistochemistry-Paraffin: SIPA1 Antibody [NBP2-20369]

Immunohistochemistry-Paraffin: SIPA1 Antibody [NBP2-20369] - Paraffin-embedded HBL435 xenograft. SIPA1 antibody [C3], C-term dilution: 1:500.

Applications for SIPA1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 40% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: SIPA1

The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date. [provided by RefSeq]

Alternate Names

GTPase-activating protein Spa-1, MGC102688, MGC17037, p130 SPA-1, signal-induced proliferation-associated 1, signal-induced proliferation-associated protein 1, Sipa-1, SPA1signal-induced proliferation-associated gene 1

Gene Symbol

SIPA1

UniProt

Additional SIPA1 Products

Product Documents for SIPA1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SIPA1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.