SIRP beta 1/CD172b Antibody (B4B6) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-09152

Clone B4B6 was used by HLDA to establish CD designation.
Novus Biologicals, part of Bio-Techne
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NBP3-09152
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Flow Cytometry

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # B4B6

Format

BSA Free

Concentration

1 mg/ml

View all SIRP beta 1/CD172b Antibodies »

Product Summary for SIRP beta 1/CD172b Antibody (B4B6) - BSA Free

Immunogen

NIH-3T3 cells transfected with human SIRP beta 1/CD172b

Specificity

The mouse monoclonal antibody B4B6 recognizes an extracellular epitope of CD172b, an approximately 50 kDa transmembrane glycoprotein expressed on myeloid cells.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for SIRP beta 1/CD172b Antibody (B4B6) - BSA Free

Flow Cytometry: SIRP beta 1/CD172b Antibody (B4B6) - BSA Free [NBP3-09152]

Flow Cytometry: SIRP beta 1/CD172b Antibody (B4B6) - BSA Free [NBP3-09152]

Flow Cytometry: SIRP beta 1/CD172b Antibody (B4B6) [NBP3-09152] - Analysis (surface staining) of human peripheral blood cells with anti-human CD172b (B4B6) purified, GAM-APC.

Applications for SIRP beta 1/CD172b Antibody (B4B6) - BSA Free

Application
Recommended Usage

Flow Cytometry

1-4 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SIRP beta 1/CD172b

The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene.

Long Name

Signal-regulatory Protein beta 1

Alternate Names

CD172b, SIRPB1

Gene Symbol

SIRPB1

Additional SIRP beta 1/CD172b Products

Product Documents for SIRP beta 1/CD172b Antibody (B4B6) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for SIRP beta 1/CD172b Antibody (B4B6) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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