SIRT7 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21247

Novus Biologicals, part of Bio-Techne
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NBP3-21247-100ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (99%), Rat (95%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Sirtuin 7/SIRT7 Antibodies »

Product Summary for SIRT7 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LVVYTGAGISTAASIPDYRGPNGVWTLLQKGRSVSAADLSEAEPTLTHMSITRLHEQKLVQHVVSQNCDGLHLRSGLPRTAISE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SIRT7 Antibody

Immunocytochemistry/Immunofluorescence: SIRT7 Antibody [NBP3-21247] -

Immunocytochemistry/Immunofluorescence: SIRT7 Antibody [NBP3-21247] -

Staining of human cell line U-2 OS shows localization to nucleoplasm & nuclear speckles.

Applications for SIRT7 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Sirtuin 7/SIRT7

SIRT7 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. SIRT7 is included in class IV. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. SIRT7 is included in class IV of the sirtuin family.

Long Name

NAD-Dependent Protein Deacetylase Sirtuin-7

Alternate Names

SIR2L7

Gene Symbol

SIRT7

Additional Sirtuin 7/SIRT7 Products

Product Documents for SIRT7 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for SIRT7 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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