SKA1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-20376

Novus Biologicals, part of Bio-Techne
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NBP2-20376
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Predicted:

Rhesus Macaque (94%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all SKA1 Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human SKA1. The exact sequence is proprietary.

Reactivity Notes

Bovine (87%).

Localization

Spindle; Kinetochore

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

29 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for SKA1 Antibody

Immunohistochemistry-Paraffin: SKA1 Antibody [NBP2-20376]

Immunohistochemistry-Paraffin: SKA1 Antibody [NBP2-20376]

Immunohistochemistry-Paraffin: SKA1 Antibody [NBP2-20376] - Paraffin-embedded rat testis. C18orf24 antibody diluted at 1:500
Immunohistochemistry-Paraffin: SKA1 Antibody [NBP2-20376]

Immunohistochemistry-Paraffin: SKA1 Antibody [NBP2-20376]

Immunohistochemistry-Paraffin: SKA1 Antibody [NBP2-20376] - Immunohistochemical analysis of paraffin-embedded gastric ca, using antibody at 1:500 dilution.
Immunohistochemistry-Paraffin: SKA1 Antibody [NBP2-20376]

Immunohistochemistry-Paraffin: SKA1 Antibody [NBP2-20376]

Immunohistochemistry-Paraffin: SKA1 Antibody [NBP2-20376] - Paraffin-embedded mouse liver. C18orf24 antibody diluted at 1:500.

Applications for SKA1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol, 1% BSA

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: SKA1

Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it mediates the interaction with microtubules.

Alternate Names

C18orf24, chromosome 18 open reading frame 24, MGC10200, spindle and kinetochore associated complex subunit 1, spindle and kinetochore-associated protein 1, spindle and KT (kinetochore) associated 1

Gene Symbol

SKA1

UniProt

Q96BD8 (Human)

Additional SKA1 Products

Product Documents for SKA1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for SKA1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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