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SLC22A1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-59464

Novus Biologicals, part of Bio-Techne
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NBP1-59464

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1 mg/ml

Product Specifications

Immunogen

Synthetic peptides corresponding to SLC22A1(solute carrier family 22 (organic cation transporter), member 1) The peptide sequence was selected from the N terminal of SLC22A1 (NP_003048). Peptide sequence LSCVDPLASLATNRSHLPLGPCQDGWVYDTPGSSIVTEFNLVCADSWKLD The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

61 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for SLC22A1 Antibody

Western Blot: SLC22A1 Antibody [NBP1-59464]

Western Blot: SLC22A1 Antibody [NBP1-59464]

Western Blot: SLC22A1 Antibody [NBP1-59464] - Sample Tissue: Jurkat, Lane A: Primary Antibody, Lane B: Primary Antibody + Blocking Peptide, Primary Antibody Concentration: 2.5ug/mL, Peptide Concentration: 8.0ug/mL, Lysate Quantity: 25ug/lane, Gel Concentration: 12%
Immunohistochemistry-Paraffin: SLC22A1 Antibody [NBP1-59464]

Immunohistochemistry-Paraffin: SLC22A1 Antibody [NBP1-59464]

Immunohistochemistry-Paraffin: SLC22A1 Antibody [NBP1-59464] - Human Intestine Tissue, antibody concentration 4-8ug/ml. Cells with positive label: Epithelial cells of intestinal villus (indicated with arrows) 400X magnification.
Western Blot: SLC22A1 Antibody [NBP1-59464]

Western Blot: SLC22A1 Antibody [NBP1-59464]

Western Blot: SLC22A1 Antibody [NBP1-59464] - Jurkat cell lysate, Antibody Titration: 2.5ug/ml

Applications for SLC22A1 Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

4-8 ug/ml

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SLC22A1

Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. SLC22A1 contains twelve putative transmembrane domains and is a plasma integral membrane protein.Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Two transcript variants encoding two different isoforms have been found for this gene, but only the longer variant encodes a functional transporter.

Long Name

Solute carrier family 22 member 1

Alternate Names

OCT1

Entrez Gene IDs

6580 (Human); 20517 (Mouse); 24904 (Rat); 519461 (Bovine); 100008659 (Rabbit)

Gene Symbol

SLC22A1

UniProt

Additional SLC22A1 Products

Product Documents for SLC22A1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SLC22A1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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