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SLC22A17 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76918

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

Product Specifications

Immunogen

Antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of the human Slc22A17. The immunogen is located within the last 50 amino acids of Slc22A17. Amino Acid Squence: CRRPSLLRQPPPTR

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Bovine (86%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

61 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for SLC22A17 Antibody - BSA Free

Western Blot: SLC22A17 AntibodyBSA Free [NBP1-76918]

Western Blot: SLC22A17 AntibodyBSA Free [NBP1-76918]

Western Blot: SLC22A17 Antibody [NBP1-76918] - Analysis in SK-N-SH lysate with antibody at 0.5 ug/mL in (A) the presence and (B) the absence of blocking peptide.
Immunocytochemistry/ Immunofluorescence: SLC22A17 Antibody - BSA Free [NBP1-76918]

Immunocytochemistry/ Immunofluorescence: SLC22A17 Antibody - BSA Free [NBP1-76918]

Immunocytochemistry/Immunofluorescence: SLC22A17 Antibody [NBP1-76918] - Analysis of SLC22A17 in mouse kidney tissue with SLC22A17 antibody at 20 ug/ml.
Immunohistochemistry-Paraffin: SLC22A17 Antibody - BSA Free [NBP1-76918]

Immunohistochemistry-Paraffin: SLC22A17 Antibody - BSA Free [NBP1-76918]

Immunohistochemistry-Paraffin: SLC22A17 Antibody [NBP1-76918] - Mouse kidney tissue with SLC22A17 antibody at 2.5 ug/ml.

Applications for SLC22A17 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Immunohistochemistry

2.5 ug/mL

Immunohistochemistry-Paraffin

2.5 ug/mL

Western Blot

0.5 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SLC22A17

The Slc22 family of organic anion and cation transporters (OATs, OCTs, OCTNs) are transmembrane proteins expressed predominantly in kidney and liver. Each contain 12 predicted alpha-helical transmembrane domains (TMDs) and one large extracellular loop between TMDs 1 and 2. Transporters of the SLC22 family function in different ways such as uniporters that mediate facilitated diffusion in either direction (OCTs), as anion exchangers (OAT1, OAT3 and URAT1), and as Na(+)/l-carnitine cotransporter (OCTN2). Slc22 family members participate in the absorption and/or excretion of drugs, xenobiotics, and endogenous compounds in intestine, liver, and kidney, and perform homeostatic functions in brain and heart. Mutations in the Slc22 family may cause specific diseases such as primary systemic carnitine deficiency or idiopathic renal hypouricemia and may change drug absorption or excretion. Recent studies show the expression of Slc22A17 as receptor for Lipocalin 2 is relatively high in hematopoietic stem cells.

Alternate Names

24p3R, BOCTNGALR3, BOIThBOIT, Brain-type organic cation transporter, Lipocalin-2 receptor, Neutrophil gelatinase-associated lipocalin receptor, NgalR, NGALR2, NGALRNGAL receptor, potent brain type organic ion transporter, solute carrier family 22 (organic cation transporter), member 17, solute carrier family 22 member 17,24p3 receptor, solute carrier family 22, member 17

Entrez Gene IDs

51310 (Human)

Gene Symbol

SLC22A17

UniProt

Additional SLC22A17 Products

Product Documents for SLC22A17 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SLC22A17 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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