SLC4A8 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-20395

Novus Biologicals, part of Bio-Techne
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NBP2-20395
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Monkey (99%), Mouse (91%), Rat (91%). Backed by our 100% Guarantee.

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all SLC4A8 Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the N-terminus region of human SLC4A8. The exact sequence is proprietary.

Reactivity Notes

Rhesus Monkey (99%).

Localization

Membrane; Multi-pass membrane protein

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

123 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for SLC4A8 Antibody

Western Blot: SLC4A8 Antibody [NBP2-20395]

Western Blot: SLC4A8 Antibody [NBP2-20395]

Western Blot: SLC4A8 Antibody [NBP2-20395] - Sample (30 ug of whole cell lysate) A: U87-MG 7. 5% SDS PAGE gel, diluted at 1:1000.

Applications for SLC4A8 Antibody

Application
Recommended Usage

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: SLC4A8

Mediates electroneutral sodium- and carbonate-dependent choride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3(-) from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3(-) into the cells. Also mediates lithium-dependent HCO3(-) cotransport. May be regulated by osmolarity.

Alternate Names

DKFZp761B2318, Electroneutral Na(+)-driven Cl-HCO3 exchanger, FLJ46462, KIAA0739, k-NBC3, Na+-driven Cl-HCO3 exchanger, NBC, NBC3electroneutral sodium bicarbonate exchanger 1, NDCBE, NDCBE1, Solute carrier family 4 member 8, solute carrier family 4, sodium bicarbonate cotransporter, member 8

Gene Symbol

SLC4A8

UniProt

Q2Y0W8 (Human)

Additional SLC4A8 Products

Product Documents for SLC4A8 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for SLC4A8 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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