SLC5A12 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-49322

Novus Biologicals, part of Bio-Techne
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NBP2-49322
NBP2-49322-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all SLC5A12 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: QGSTHAGGFHNVLEQSTNGSRLHIFDFDVDPLRRH

Reactivity Notes

Mouse, Rat (80%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SLC5A12 Antibody

Immunohistochemistry-Paraffin: SLC5A12 Antibody [NBP2-49322]

Immunohistochemistry-Paraffin: SLC5A12 Antibody [NBP2-49322]

Immunohistochemistry-Paraffin: SLC5A12 Antibody [NBP2-49322] - Staining in human kidney and skin tissues.. Corresponding SLC5A12 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: SLC5A12 Antibody [NBP2-49322]

Immunohistochemistry-Paraffin: SLC5A12 Antibody [NBP2-49322]

Immunohistochemistry-Paraffin: SLC5A12 Antibody [NBP2-49322] - Staining of human lymph node shows no positivity in non-germinal center cells as expected.
Immunohistochemistry-Paraffin: SLC5A12 Antibody [NBP2-49322]

Immunohistochemistry-Paraffin: SLC5A12 Antibody [NBP2-49322]

Immunohistochemistry-Paraffin: SLC5A12 Antibody [NBP2-49322] - Staining of human small intestine shows weak to moderate membranous positivity in glandular cells.
View 2 more images

Applications for SLC5A12 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

Reported in scientific literature (PMID: 31708446)

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SLC5A12

Normal blood lactate is maintained at about 1.5 mM, and little filtered lactate is excreted in urine. Reabsorption oflactate is mediated by the low-affinity Na(+)-coupled lactate transporter SLC5A12 in the initial part of the proximaltubule and by the high-affinity Na(+)-coupled lactate transporter SLC5A8 (MIM 608044) in the distal proximal tubule(Gopal et al., 2007 (PubMed 17692818)).(supplied by OMIM)

Alternate Names

Electroneutral sodium monocarboxylate cotransporter, Low-affinity sodium-lactate cotransporter, MGC52019, SMCT2DKFZp564G223, sodium-coupled monocarboxylate transporter 2, sodium-iodide related cotransporter, solute carrier family 5 (sodium/glucose cotransporter), member 12, Solute carrier family 5 member 12

Gene Symbol

SLC5A12

Additional SLC5A12 Products

Product Documents for SLC5A12 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for SLC5A12 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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