SLC5A5/Sodium Iodide Symporter Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-62517

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all SLC5A5 Antibodies »

Product Specifications

Immunogen

Synthetic peptides corresponding to SLC5A5(solute carrier family 5 (sodium iodide symporter), member 5) The peptide sequence was selected from the middle region of SLC5A5. Peptide sequence PSEQTMRVLPSSAARCVALSVNASGLLDPALLPANDSSRAPSSGMDASRP The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

69 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for SLC5A5/Sodium Iodide Symporter Antibody

Western Blot: SLC5A5/Sodium Iodide Symporter Antibody [NBP1-62517]

Western Blot: SLC5A5/Sodium Iodide Symporter Antibody [NBP1-62517]

Western Blot: SLC5A5/Sodium Iodide Symporter Antibody [NBP1-62517] - Titration: 0.2-1 ug/ml, Positive Control: 293T cell lysate.

Applications for SLC5A5/Sodium Iodide Symporter Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SLC5A5

The sodium-iodide symporter (NIS, or SLC5A5) is a key plasma membrane protein that mediates active I- uptake in thyroid, lactating breast, and other tissues with an electrogenic stoichiometry of 2 Na+ per I-. In thyroid, NIS-mediated I- uptake is the first step in the biosynthesis of iodine-containing thyroid hormones.The sodium-iodide symporter (NIS, or SLC5A5) is a key plasma membrane protein that mediates active I- uptake in thyroid, lactating breast, and other tissues with an electrogenic stoichiometry of 2 Na+ per I-. In thyroid, NIS-mediated I- uptake is the first step in the biosynthesis of iodine-containing thyroid hormones (Dohan et al., 2007 [PubMed 18077370]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Long Name

Solute Carrier Family 5 (Sodium Iodide Symporter), Member 5

Alternate Names

NIS, TDH1

Gene Symbol

SLC5A5

UniProt

Q92911

Additional SLC5A5 Products

Product Documents for SLC5A5/Sodium Iodide Symporter Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for SLC5A5/Sodium Iodide Symporter Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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