SLC6A3/DAT1 Antibody (CL3123)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-46649

Novus Biologicals, part of Bio-Techne
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NBP2-46649
NBP2-46649-25ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL3123

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all SLC6A3/DAT1 Antibodies »

Product Summary for SLC6A3/DAT1 Antibody (CL3123)

Immunogen

Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence LHYLFSSFTTELPWNNSWNSPNCSDAHPGDSSGDSSGLNDTFGTTPAAEYFERGVLHLHQSHGIDDLG

Epitope

ELPWIHCNNSWNSPN

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for SLC6A3/DAT1 Antibody (CL3123)

Immunohistochemistry-Paraffin: SLC6A3/DAT1 Antibody (CL3123) [NBP2-46649]

Immunohistochemistry-Paraffin: SLC6A3/DAT1 Antibody (CL3123) [NBP2-46649]

Immunohistochemistry-Paraffin: SLC6A3/DAT1 Antibody (3123) [NBP2-46649] - Analysis of human pancreas shows absence of immunoreactivity (negative control).
Immunohistochemistry: SLC6A3/DAT1 Antibody (CL3123) [NBP2-46649]

Immunohistochemistry: SLC6A3/DAT1 Antibody (CL3123) [NBP2-46649]

Immunohistochemistry: SLC6A3/DAT1 Antibody (3123) [NBP2-46649] - Staining of rat striatum shows strong immunoreactivity in dopaminergic fibers.
Immunohistochemistry: SLC6A3/DAT1 Antibody (CL3123) [NBP2-46649]

Immunohistochemistry: SLC6A3/DAT1 Antibody (CL3123) [NBP2-46649]

Immunohistochemistry: SLC6A3/DAT1 Antibody (3123) [NBP2-46649] - Staining of mouse striatum shows strong immunoreactivity in dopaminergic fibers.
View 4 more images

Applications for SLC6A3/DAT1 Antibody (CL3123)

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SLC6A3/DAT1

The Dopamine Transporter (DAT) is responsible for the reaccumulation of dopamine after it has been released. DAT antibodies and antibodies for other markers of catecholamine biosynthesis are widely used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999). Levels of DAT protein expression are altered by chronic drug administration (Wilson et al., 1996).

Long Name

Dopamine Transporter

Alternate Names

DAT1, SLC6A3, VNTR

Entrez Gene IDs

6531 (Human)

Gene Symbol

SLC6A3

UniProt

Q01959 (Human)

Additional SLC6A3/DAT1 Products

Product Documents for SLC6A3/DAT1 Antibody (CL3123)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for SLC6A3/DAT1 Antibody (CL3123)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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