Slit2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-80742

Novus Biologicals, part of Bio-Techne
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NBP1-80742
NBP1-80742-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Rat, Fish - Danio rerio (Zebrafish)

Predicted:

Mouse (94%), Rat (97%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Slit2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LYINSELQDFQKVPMQTGILPGCEPCHKKVCAHGTCQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKCVHGTCLPINAFSYSCKCLE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Slit2 Antibody

Immunohistochemistry-Paraffin: Slit2 Antibody [NBP1-80742]

Immunohistochemistry-Paraffin: Slit2 Antibody [NBP1-80742]

Immunohistochemistry-Paraffin: Slit2 Antibody [NBP1-80742] - Staining of human testis shows strong cytoplasmic positivity in Leydig cells.
Immunohistochemistry-Paraffin: Slit2 Antibody [NBP1-80742]

Immunohistochemistry-Paraffin: Slit2 Antibody [NBP1-80742]

Immunohistochemistry-Paraffin: Slit2 Antibody [NBP1-80742] - Staining of human lung shows strong cytoplasmic positivity in macrophages.
Immunohistochemistry-Paraffin: Slit2 Antibody [NBP1-80742]

Immunohistochemistry-Paraffin: Slit2 Antibody [NBP1-80742]

Immunohistochemistry-Paraffin: Slit2 Antibody [NBP1-80742] - Staining of human prostate shows strong cytoplasmic positivity in smooth muscle cells.
View 1 more images

Applications for Slit2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Slit2

Slit proteins are ligands at the Roundabout (Robo) receptors and act as guidance cues in axonal migration/navigation during neural development, at the ventral midline of the neural tube. Slit1 and Slit2 are essential for midline guidance in the forebrain by acting as repulsive signals preventing inappropriate midline crossing by axons projecting from the olfactory bulb. A number of cleavage products are reported in the literature for Slit2 protiens (following alternate splicing). The C-terminal cleavage proteins are more diffusible than the larger N-terminal protein that is more tightly cell associated. Slit2 protein is expressed in fetal lung and kidney, and adult spinal cord. Weak expression in adult adrenal gland, thyroid, trachea.

Long Name

SLIT Homolog 2

Alternate Names

SLIL3

Entrez Gene IDs

9353 (Human)

Gene Symbol

SLIT2

UniProt

O94813

Additional Slit2 Products

Product Documents for Slit2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Slit2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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