Smad4 Antibody (SMAD4/2440) [DyLight 680]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-08320FR

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Unconjugated

NBP3-07262

Alexa Fluor 350

NBP3-08320AF350

Alexa Fluor 405

NBP3-08320AF405

Alexa Fluor 488

NBP3-08320AF488

Alexa Fluor 532

NBP3-08320AF532

Alexa Fluor 594

NBP3-08320AF594

Alexa Fluor 647

NBP3-08320AF647

Alexa Fluor 700

NBP3-08320AF700

Alexa Fluor 750

NBP3-08320AF750

Allophycocyanin

NBP3-08320APC

Biotin

NBP3-08320B

CoraFluor 1

NBP3-08320CL1

DyLight 350

NBP3-08320UV

DyLight 405

NBP3-08320V

DyLight 488

NBP3-08320G

DyLight 550

NBP3-08320R

DyLight 594

NBP3-08320DL594

DyLight 650

NBP3-08320C

DyLight 755

NBP3-08320IR

FITC

NBP3-08320F

HRP

NBP3-08320H

Janelia Fluor 525

NBP3-08320JF525

Janelia Fluor 549

NBP3-08320JF549

Janelia Fluor 585

NBP3-08320JF585

Janelia Fluor 635

NBP3-08320JF635

Janelia Fluor 646

NBP3-08320JF646

Janelia Fluor 669

NBP3-08320JF669

PE

NBP3-08320PE

PerCP

NBP3-08320PCP

Forumulation

Catalog #

Azide and BSA Free

NBP3-08320

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin, Protein Array

Label

DyLight 680 (Excitation = 692 nm, Emission = 712 nm)

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # SMAD4/2440

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Smad4 Antibodies »

Product Specifications

Immunogen

Recombinant full-length human Smad4 protein (Uniprot: Q13485 )

Localization

Cytoplasmic & Nuclear

Marker

Pancreatic Adenocarcinoma Marker

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Applications for Smad4 Antibody (SMAD4/2440) [DyLight 680]

Application

Recommended Usage

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Protein Array

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Smad4

Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad) have been implicated as downstream effectors of TGFbeta/BMP signaling. Smad1 (also designated Madr1 or JV4-1), Smad5 and mammalian Smad8 (also designated Smad9 or MadH6) are effectors of BMP2 and BMP4 function while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGFbeta and activin-mediated growth modulation. Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGFbeta signaling by interfering with TGFbeta-mediated phosphorylation of other Smad family members.

Long Name

Mothers Against DPP Homolog 4

Alternate Names

DPC4, MADH4

Gene Symbol

SMAD4

Additional Smad4 Products

Product Documents for Smad4 Antibody (SMAD4/2440) [DyLight 680]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for Smad4 Antibody (SMAD4/2440) [DyLight 680]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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