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SMG6 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-92410

Novus Biologicals, part of Bio-Techne
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NBP1-92410
NBP1-92410-25ul

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for SMG6 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: MAEGLERVRISASELRGILATLAPQAGSRENMKELKEARPRKDNRRPDLEIYKPGLSRLRNKPKIKEPPGSEEFKDEIVNDRDCSAVENGTQPVKDVCKELNNQEQNGPIDP

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (84%), Rat (85%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SMG6 Antibody

Immunocytochemistry/ Immunofluorescence: SMG6 Antibody [NBP1-92410]

Immunocytochemistry/ Immunofluorescence: SMG6 Antibody [NBP1-92410]

Immunocytochemistry/Immunofluorescence: SMG6 Antibody [NBP1-92410] - Staining of human cell line U-251 MG shows localization to nucleoli.
Immunohistochemistry-Paraffin: SMG6 Antibody [NBP1-92410]

Immunohistochemistry-Paraffin: SMG6 Antibody [NBP1-92410]

Immunohistochemistry-Paraffin: SMG6 Antibody [NBP1-92410] - Staining of human cerebellum shows distinct cytoplasmic and nucleolar/ nuclear positivity in Purkinje cells.

Applications for SMG6 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SMG6

SMG6 is involved in nonsense-mediated mRNA decay (Fukuhara et al., 2005 (PubMed 15721257)).(supplied by OMIM)

Alternate Names

C17orf31, EST1 telomerase component homolog A, EST1A, EST1-like protein A, ever shorter telomeres 1A, hSmg5/7a, KIAA0732, SMG-6, smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans), telomerase subunit EST1A, telomerase-binding protein EST1A

Entrez Gene IDs

23293 (Human)

Gene Symbol

SMG6

UniProt

Additional SMG6 Products

Product Documents for SMG6 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SMG6 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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