SMG7 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-22967

Novus Biologicals, part of Bio-Techne
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NBP1-22967
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Key Product Details

Validated by

Independent Antibodies, Biological Validation

Species Reactivity

Validated:

Human, Mouse

Cited:

Human

Applications

Validated:

Immunoprecipitation, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.2 mg/ml

View all SMG7 Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 1087 and 1137 of human suppressor with morphogenetic effect on genitalia protein 7 (ever shorter telomeres 1C) using the numbering given in entry NP_775179.1 (GeneID 9887).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SMG7 Antibody

Western Blot: SMG7 Antibody [NBP1-22967]

Western Blot: SMG7 Antibody [NBP1-22967]

Western Blot: SMG7 Antibody [NBP1-22967] - Western Blot and Immunoprecipitation: by Western Blot : Whole cell lysate from HeLa, 293T and mouse NIH3T3 cells. SMG7 was also immunoprecipitated byanother rabbit anti-SMG7 antibody.

Applications for SMG7 Antibody

Application
Recommended Usage

Immunoprecipitation

5-15 ug/mg lysate

Western Blot

1:2000-1:10000
Application Notes
Western blot of lysates performed using standard western blot reagents and 4-8% SDS-PAGE.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

TBS and 0.1% BSA

Preservative

0.09% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: SMG7

SMG7 plays a role in the dephosphorylation of UPF1, an RNA-dependent ATPase and helicase critical to nonsense-mediated mRNA decay (NMD). It is a homolog of the C. elegans NMD factor Smg7 (suppressor with morphogenetic effect on genitalia protein 7). SMG7 functions as an adaptor to target protein phosphatase 2A to UPF1 for dephosphorylation of UPF1.

Alternate Names

breast cancer-associated antigen SGA-56M, C1orf16, chromosome 1 open reading frame 16, EST1 telomerase component homolog C, EST1CKIAA0250SGA56M, EST1-like protein C, ever shorter telomeres 1C, FLJ23717, hSMG-7, protein SMG7, SMG-7, SMG-7 homolog, Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)

Entrez Gene IDs

9887 (Human)

Gene Symbol

SMG7

UniProt

NP_775179.1 (Human)

Additional SMG7 Products

Product Documents for SMG7 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for SMG7 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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