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SMN2 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-94596

Novus Biologicals, part of Bio-Techne
Catalog #
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NBP2-94596-0.02ml
NBP2-94596-0.1ml

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-197 of human SMN2 (NP_059107.1). MAMSSGGSGGGVPEQEDSVLFRRGTGQSDDSDIWDDTALIKAYDKAVASFKHALKNGDICETSGKPKTTPKRKPAKKNKSQKKNTAASLQQWKVGDKCSAIWSEDGCIYPATIASIDFKRETCVVVYTGYGNREEQNLSDLLSPICEVANNIEQNAQENENESQVSTDESENSRSPGNKSDNIKPKSAPWNSFLPPP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SMN2 Antibody - BSA Free

Western Blot: SMN2 AntibodyBSA Free [NBP2-94596]

Western Blot: SMN2 AntibodyBSA Free [NBP2-94596]

Western Blot: SMN2 Antibody [NBP2-94596] - Western blot analysis of extracts of various cell lines, using SMN2 Rabbit pAb (NBP2-94596) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Western Blot: SMN2 AntibodyBSA Free [NBP2-94596]

Western Blot: SMN2 AntibodyBSA Free [NBP2-94596]

Western Blot: SMN2 Antibody [NBP2-94596] - Analysis of 200ug extracts of 293T cells, using SMN2 at a dilition of 1:1000.

Applications for SMN2 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Immunoprecipitation

1:50-1:100

Western Blot

1:500 - 1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.3), 50% glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: SMN2

Gemin 1 (SMN) is the central component of a large oligomeric complex (SMN complex), including Gemins 2-7, that is necessary and sufficient for the in vivo assembly of Sm proteins onto the small nuclear (sn)RNAs that mediate pre-mRNA splicing. The SMN complex is found in the cytoplasm and nucleus. Within the nucleus, this protein localizes to subnuclear bodies called gems which are found near coiled bodies containing high concentrations of small ribonucleoproteins (snRNPs). Spinal muscular atrophy, a motor neuron disorder, results from reduced levels or a mutation in the Gemin 1 protein.

Alternate Names

BCD541, C-BCD541, Component of gems 1, FLJ76644, gemin 1, gemin-1, MGC20996, MGC5208, SMN, SMNCSMN1, SMNT, survival motor neuron protein, survival of motor neuron 2, centromeric

Gene Symbol

SMN2

Additional SMN2 Products

Product Documents for SMN2 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SMN2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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