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SNAP25 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB300-737

Novus Biologicals, part of Bio-Techne
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NB300-737

Key Product Details

Species Reactivity

Validated:

Rat

Predicted:

Bovine (100%), Canine (100%), Chicken (100%), Guinea Pig (100%), Human (100%), Mouse (100%), Primate (100%), Zebrafish (100%). Backed by our 100% Guarantee.

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for SNAP25 Antibody

Immunogen

Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH. Accession # P60881

Reactivity Notes

It is anticipated that the antibody will work with bovine, canine, chicken, guinea pig, human, mouse, non-human primate and Zebra fish tissue due to the fact that these species have 100 % homology with the amino acid sequence used as antigen.

Specificity

Specific for endogenous levels of the ~25 kDa SNAP25 protein.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

25 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for SNAP25 Antibody

Western Blot: SNAP25 Antibody [NB300-737]

Western Blot: SNAP25 Antibody [NB300-737]

Western Blot: SNAP25 Antibody [NB300-737] - Rat cortex lysate showing specific labeling of the ~25k SNAP25 protein.

Applications for SNAP25 Antibody

Application
Recommended Usage

Western Blot

1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

10mM HEPES (pH 7.5), 0.15M NaCl, 0.1 mg/ml BSA and 50% Glycerol

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: SNAP25

SNAP25 (Synaptosomal associated protein of 25 kDa) is a presynaptic plasma membrane protein that is widely distributed throughout the brain and involved in the regulation of neurotransmitter release. Decreased levels of SNAP25 have been found in the brains of patients with Down Syndrome and Alzheimer's Disease (Greber et al.,1999). In addition, a significant reduction in the hippocampal expression of SNAP25 has also been found in patients with Schizophrenia (Fatemi et al., 2001).

Long Name

Synaptosomal-associated Protein, 25 kDa

Alternate Names

RIC4, SEC9, SUP

Entrez Gene IDs

20614 (Mouse); 25012 (Rat)

Gene Symbol

SNAP25

UniProt

Additional SNAP25 Products

Product Documents for SNAP25 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SNAP25 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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