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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # OTI2A5

Concentration

1 mg/ml

Product Summary for SNRPB2 Antibody (OTI2A5)

Immunogen

Full length human recombinant protein of human SNRPB2 (NP_937863) produced in E.coli.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

25.3 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for SNRPB2 Antibody (OTI2A5)

Western Blot: SNRPB2 Antibody (OTI2A5) [NBP2-45893]

Western Blot: SNRPB2 Antibody (OTI2A5) [NBP2-45893]

Western Blot: SNRPB2 Antibody (2A5) [NBP2-45893] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SNRPB2.
Immunohistochemistry: SNRPB2 Antibody (OTI2A5) [NBP2-45893]

Immunohistochemistry: SNRPB2 Antibody (OTI2A5) [NBP2-45893]

Immunohistochemistry: SNRPB2 Antibody (2A5) [NBP2-45893] - Analysis of Carcinoma of Human bladder tissue. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120C for 3 min)
Immunohistochemistry: SNRPB2 Antibody (OTI2A5) [NBP2-45893]

Immunohistochemistry: SNRPB2 Antibody (OTI2A5) [NBP2-45893]

Immunohistochemistry: SNRPB2 Antibody (2A5) [NBP2-45893] - Analysis of Human pancreas tissue. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120C for 3 min)

Applications for SNRPB2 Antibody (OTI2A5)

Application
Recommended Usage

Immunohistochemistry

1:150

Immunohistochemistry-Paraffin

1:150

Western Blot

1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: SNRPB2

The protein encoded by the SNRPB2 gene associates with stem loop IV of U2 small nuclear ribonucleoprotein (U2 snRNP) in the presence of snRNP-A'. The encoded protein may play a role in pre-mRNA splicing. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding the same protein have been found for this gene. (provided by RefSeq)

Alternate Names

MGC24807, MGC45309, Msl1, small nuclear ribonucleoprotein polypeptide B, small nuclear ribonucleoprotein polypeptide B'', small nuclear ribonucleoprotein polypeptide B2, U2 small nuclear ribonucleoprotein B'', U2 snRNP B''

Gene Symbol

SNRPB2

Additional SNRPB2 Products

Product Documents for SNRPB2 Antibody (OTI2A5)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SNRPB2 Antibody (OTI2A5)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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