SNX15 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-1210

Novus Biologicals, part of Bio-Techne
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NB100-1210
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Key Product Details

Species Reactivity

Human

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all SNX15 Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-EEILRLHLSQLPP corresponding to C-Terminus according to NP_037438.2, NP_680086.2.

Specificity

This antibody is expected to recognise both Human isoforms according to NP_037438.2 and NP_680086.2.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for SNX15 Antibody

Western Blot: SNX15 Antibody [NB100-1210]

Western Blot: SNX15 Antibody [NB100-1210]

Western Blot: SNX15 Antibody [NB100-1210] - (0.5ug/ml) of 293 lysate (RIPA buffer, 30ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

Applications for SNX15 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:8000

Western Blot

1:1000
Application Notes
WB: Approx. 48 kDa band observed in human kidney lysates and in HEK293 lysates (calculated MW 38.2 kDa band according to NP_037438.2). Note: A single approx. 30-35 kDa band (probably representing the shorter isoform) was observed in human heart.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: SNX15

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. This gene encodes two transcript variants encoding distinct isoforms.

Alternate Names

clone iota unknown protein, HSAF001435, sorting nexin 15, sorting nexin-15

Entrez Gene IDs

29907 (Human)

Gene Symbol

SNX15

UniProt

NP_037438 (Human)

Additional SNX15 Products

Product Documents for SNX15 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for SNX15 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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