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SNX2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-25150

Novus Biologicals, part of Bio-Techne
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NBP3-25150

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (94%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for SNX2 Antibody

Immunogen

This antibody has been engineered to specifically recognize the recombinant protein SNX2 using the following amino acid sequence: SPSSPEPASLPAEDISANSNGPKPTEVVLDDDREDL

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SNX2 Antibody

SNX2 Antibody Immunocytochemistry/Immunofluorescence: SNX2 Antibody [NBP3-25150]

Immunocytochemistry/Immunofluorescence: SNX2 Antibody [NBP3-25150]

Staining of human cell line HAP1 shows localization to endosomes.

Applications for SNX2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 µg/ml
Application Notes
For ICC/IF, we recommend using a combination of PFA and Triton X-100. This will give you the optimal results for your experiments.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SNX2

SNX2 (Sorting nexin 2) is a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. SNX2 is a component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. It may form oligomeric complexes with family members.

Alternate Names

MGC5204, sorting nexin 2, sorting nexin-2, Transformation-related gene 9 protein, TRG-9

Gene Symbol

SNX2

Additional SNX2 Products

Product Documents for SNX2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SNX2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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